Radiation-induced pathological fractures of the proximal femur: a case series considering an endoprosthetic solution

ABSTRACT BACKGROUND: Radiation-induced pathological fractures of the proximal femur are difficult to treat due frequent non-union and hardware failure using standard fracture fixation techniques. This case series investigates endoprosthetic replacement as a treatment option METHODS: A retrospective folder review from private hospital in Cape Town, patients who had sustained radiation-induced fracture, was reviewed descriptive statistics. RESULTS: Six met inclusion criteria. One patient excluded minimum follow-up time six months not met. Of Ave that were analysed, all transverse, subtrochanteric fractures. Prior definitive with femoral replacement, three treated trauma instrumentation prior referral unit, one vascularised fibular graft their initial while at unit. an first procedure Among graft, there 100% rate. ablation free musculocutaneous flap periprosthetic infection after replacement. only complication At median 15 (min 7, max 55) Musculoskeletal Tumour Society score 74% 63%, 93%. CONCLUSION: seeks highlight high rates seen when treating this condition or biological methods. Further research is needed, but may be viable alternative solution Level evidence: 4. Keywords: